22Rv1（人前列腺癌細(xì)胞）
CBP60341
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| I. General information | |
| Synonyms: | 22Rv1 |
| Background: | 22Rv1 is a human prostate carcinoma epithelial cell line derived from a xenograft that was serially propagated in mice after castration-induced regression and relapse of the parental, androgen-dependent CWR22 xenograft. |
| Species: | Homo sapiens, human |
| Tissue: | prostate |
| Disease: | carcinoma |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Doubling Time: | 40 hours |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 10,11 D13S317: 9,12 D16S539: 12 D5S818: 11,12,13 D7S820: 9,10,11 THO1: 6,9.3 TPOX: 8 vWA: 15,21 Our Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+10%FBS 22Rv1完全培養(yǎng)基，# CBP60341M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | prostate specific antigen (PSA) |
| Receptor Expression: | androgen receptor |
| Tumor Formation: | Yes, forms tumors in nude mice |
| Comments: | The cell line expresses prostate specific antigen (PSA). Growth is weakly stimulated by dihydroxytestosterone and lysates are immunoreactive with androgen receptor antibody by Western blot analysis. Growth is stimulated by epidermal growth factor (EGF) but is not inhibited by transforming growth factor beta-1 (TGF beta- 1). Recently , it has been shown that 22Rv1 prostate carcinoma cells produce high-titer of the human retrovirus XMRV (xenotropic murine leukemia virus-related virus). For more information, please contact us(4008-750-250). |
