NOD2 Effector Reporter Cell
CBP74536
詢 價
索取Protocol
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Background | |
| NOD2是一種存在于免疫細胞內(nèi)的重要受體蛋白，它能識別細菌的特定成分并激活免疫反應(yīng)，是先天性免疫系統(tǒng)的關(guān)鍵分子。某些NOD2基因的變異會增加患克羅恩病等炎癥性腸病的風(fēng)險。 | |
| II. Description | |
| NOD2 Effector Reporter Cell 報告基因藥靶模型很好的模擬了體內(nèi) NOD2基的信號轉(zhuǎn)導(dǎo)過程。 | |
| III. Introduction | |
| Expressed gene: | NOD2 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | MEM +10%FBS + 1% NEAA+ 1mM NaP+1 μg/ml Puromycin+ 100 μg/ml Hygromycin B |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| IV. Representative Data | |
 Figure 1. Dose Response of L18-MDP in NOD2 Effector Reporter Cell (C38). |
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