Claudin18.2/NUGC4
CBP74135
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Background | |
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Claudin18是位于細胞膜表面緊密連接的主要成分，它在維持細胞極性和屏障功能以及促進耐酸能力方面起著重要作用。CLDN18的第一個外顯子可以選擇性剪接，形成兩個具有高度同源氨基酸序列的不同剪接突變體(CLDN18.1和CLDN18.2)?？缒さ鞍證LDN18由兩個細胞外環(huán)、四個跨膜結(jié)構(gòu)域和一個細胞質(zhì)結(jié)構(gòu)域組成。 |
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| II. Description | |
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Claudin18.2 NUGC4 細胞，在 NUGC4 細胞的基礎上，穩(wěn)定表達人 Claudin18.2。 |
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| III. Introduction | |
| Host Cell: |
NUGC4 |
| Expressed gene: |
Claudin18.2 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+20%FBS+2μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Description of Host Cell Line | |
| Species: | Homo sapiens, human |
| Tissue: | gastric lymph node |
| Disease: | signet ring cell carcinoma |
| Morphology: | spherical |
| Growth Properties: | Adherent |
| V. Representative Data | |
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1. Claudin18.2/NUGC4 |
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